Dr. Walid A. Houry is Professor in the Department of Biochemistry and in the Department of Chemistry at the University of Toronto. Dr. Houry obtained his MSc (1991) and PhD (1996) from Cornell University and then did his postdoctoral training at the Sloan-Kettering Institute (1996-1997) in New York City and at the Max-Planck-Institute for Biochemistry (1997-2000) in Munich, Germany. He is interested in the general area of cellular stress responses and the role of molecular chaperones and ATP-dependent proteases in these responses. Dr. Houry is also heavily involved in the general scientific community in several capacities.

Research Synopsis

The ultimate aim of our projects is to address the fundamental question of how molecular chaperones and ATP-dependent proteases modulate protein folding in the cell.  To this end, the group utilizes various structural, biophysical, biochemical, proteomic, and cell biological approaches to understand the mechanism of function of these chaperones and proteases. We are also interested in the development of novel anticancers and antibiotics by identifying compounds that target these chaperones and proteases and result in the dysregulation of protein homeostasis in the cell.

Learn more: Houry Lab

Publications

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Professor of Biochemistry, University of Toronto

Professor of Chemistry, University of Toronto

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